In this issue of Veterinary Clinics: Small Animal Practice, guest editors Drs. Felix Duerr and Lindsay Elam bring their considerable expertise to the topic of Small Animal Orthopedic Medicine. Mobility and orthopedic challenges are common issues that can negatively impact the quality of life and overall health of small animal companion pets. This issue covers a wide range of topics to help practicing veterinarians identify, assess, treat, and manage orthopedic and mobility issues in pets. Contains 15 relevant, practice-oriented topics including canine mobility maintenance and promotion of a healthy lifestyle; joint injection techniques and indications; platelet-rich plasma as an orthobiologic: physical rehabilitation; and more. Provides in-depth clinical reviews on small animal orthopedic medicine, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.